The Simpsons

Wouldn't normally plug Nature content here, but there's an interview with Al Jean in this week's Nature Podcast that's worth a listen (it's only five minutes long). It'll also appear in the print edition.

Piltdown angel: In "Lisa the Skeptic" an almost complete human skeleton with angel's wings pits science — Lisa and guest star Stephen Jay Gould — against faith, as defended by Ned Flanders: "Science is like a blabbermouth who ruins a movie by telling you how it ends. Well I say that there are some things we don't want to know. Important things!" - from the top ten science moments in the Simpsons

Didn't think much of the trailer but apparently the film is brilliant.

Physics World covered science in the Simpsons too. A quick Google search also turns up this introduction to physics that uses scences from the Simpsons as a jumping off point. Not convinced that there's a market for Simpsons themed physics textbooks myself but hey...