BIND goes on the offensive?

My knowledge of patent law (U.S patent law, at that) is rather sketchy, but I was surprised to read (via Snowdeal) that Unleashed Informatics - the commercial spinoff from the now defunct Blueprint Initiative - is planning on enforcing a patent it holds covering "a system for electronically managing, finding, and/or visualizing biomolecular interactions comprising a computer system including at least one computer receiving data on biomolecular interactions from a plurality of providers" (full patent here). To be fair, Unleashed has said that it will only target for-profit organizations.

Of course companies have to protect their intellectual property, and I don't have any problem with that. Some points that concerned me, though:

It's a software patent. Fine, patent software ideas so that somebody else can't patent it after you and then take you to court, but enforcing it yourself? Seems dodgy, and it's not like there are hundreds of competitive commercial BIND clones out there (AFAIK). Are UI under pressure from funders, do they just need a quick buck, what?

Surely US-based databases like Reactome fall under the patent - are they effectively at the mercy of Unleased Informatics deciding to be nice to academics? What happens if UI goes bust and the patent rights are acquired by a company not so nice?